One of the original Twelve Apostles of Jesus, Bartholomew allegedly met his martyred end in Albanopolis, Armenia during the first century C.E. By some accounts, he was merely beheaded, but popular tradition holds that he was flayed alive and crucified upside-down.
You'll also spot his flayed skin in Michelangelo's The Last Judgment, pictured to the right. Interestingly enough, depictions of the saint often echo that of the Greek hero Hercules, who often holds the skin of the Nemean Lion.
You'll find this statue of St. Bartholomew within the Duomo Cathedral of Milan. The photo below reveals the face and scalp slung behind him. It's quite a stunning statue -- one that repulsed and fascinated author Mark Twain during his travels. There's something perfectly inhuman about the depiction of his impossible body.